SCHEMBL666288

SCHEMBL666288

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)n(C)c1=O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.46
▸ SLC28A2 O43868 1/20 0.46
▸ SLC29A1 Q99808 1/20 0.46
▸ SLC28A3 Q9HAS3 1/20 0.46
▸ LMNA P02545 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ MTOR P42345 1/20 0.42
▸ MDM2 Q00987 1/20 0.42
▸ NCOA1 Q15788 1/20 0.42
▸ NCOA3 Q9Y6Q9 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ MAPT P10636 1/20 0.39
▸ CDA P32320 1/20 0.39
▸ SLC5A2 P31639 1/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21980556 1.00 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL30591063 0.99 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL26109184 0.92 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL23869401 0.90 UMPS (0.36) SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL31685475 0.88 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL23666552 0.88 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL8402713 0.86 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL8402712 0.86 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL18574266 0.86 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3LMNA
SCHEMBL14929312 0.86 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2558 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 — — US claimed
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 — — US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 — — EP claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2025-09-25 — — US claimed
US-20250277223-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2025-09-04 — — US claimed
US-12398379-B2 Compositions and methods for treating ornithine transcarbamylase deficiency ARCTURUS THERAPEUTICS, INC. (US) 2025-08-26 — — US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 — — US claimed
EP-4598935-A2 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2025-08-13 — — EP claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 — — WO claimed
CN-110719787-A RNA for treating autoimmune diseases 生物技术RNA制药有限公司 2020-01-21 — — CN claimed
EP-3387150-B1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY NOVARTIS AG (CH) 2019-10-02 — — EP claimed
US-20190175690-A1 COMPOSITIONS AND METHODS FOR CARDIAC REPAIR CHILDREN'S MEDICAL CENTER CORPORATION (US) 2019-06-13 — — US claimed
EP-3460064-A1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) The General Hospital Corporation d/b/a Massachusetts General Hospital (US) 2019-03-27 — — EP claimed
US-10086043-B2 Efficient protein expression in vivo using modified RNA (MOD-RNA) THE GENERAL HOSPITAL CORPORATION (US) 2018-10-02 — — US claimed
EP-2694660-B1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) MASSACHUSETTS GEN HOSPITAL (US) 2018-08-08 — — EP claimed
US-9719084-B2 Co-transcriptional assembly of modified RNA nanoparticles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2017-08-01 — — US claimed
US-20150203842-A1 CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-07-23 — — US claimed
US-20140073687-A1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) IMMUNE DISEASE INSTITUTE, INC. (US) 2014-03-13 — — US claimed
EP-2578685-A2 RNA containing modified nucleosides and methods of use thereof The Trustees of The University of Pennsylvania (US) 2013-04-10 — — EP claimed
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