Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357669 | 1.00 | KMT2A (0.55) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL23647519 | 0.86 | KMT2A (0.52) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29362781 | 0.86 | KMT2A (0.52) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL8875045 | 0.86 | FFAR1 (0.45) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29365592 | 0.82 | ALDH1A1 (0.47) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL23647586 | 0.80 | POLB (0.45) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL29366024 | 0.80 | POLB (0.45) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL30201901 | 0.77 | POLB (0.54) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL3576904 | 0.75 | GAA (0.56) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL19961833 | 0.75 | GAA (0.56) | KMT2AMEN1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979907-A | Cyclohexane-1, 3-dione compound and application thereof | 郑州恒诚仪器耗材有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113973824-A | Use of cyclohexane-1, 3-diones as herbicides | 郑州恒诚仪器耗材有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111205208-B | Cyclohexane-1, 3-diketone compound and synthetic method and application thereof | 郑州恒诚仪器耗材有限公司 | 2021-12-17 | — | — | CN | disclosed |
| WO-2021143617-A1 | CYCLOHEXADIENE OXIME ETHER COMPOUND, SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF | 郑州手性药物研究院有限公司 | 2021-07-22 | — | — | WO | disclosed |
| CN-111205208-A | Cyclohexane-1, 3-diketone compound and synthetic method and application thereof | 郑州手性药物研究院有限公司 | 2020-05-29 | — | — | CN | disclosed |