Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366729 | 1.00 | TP53 (0.37) | TP53LMNAMAPTKIF18AIDH1 | |
| Hydrochloric Acid SCHEMBL2542337 | 0.99 | TP53 (0.37) | TP53LMNAMAPTKIF18AIDH1 | |
| Hydrochloric Acid SCHEMBL2542331 | 0.99 | TP53 (0.37) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2372513 | 0.98 | TP53 (0.39) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2372519 | 0.98 | TP53 (0.39) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2366299 | 0.91 | IDH1 (0.33) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2366293 | 0.91 | IDH1 (0.33) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2545849 | 0.91 | IDH1 (0.34) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2365780 | 0.91 | IDH1 (0.34) | TP53LMNAMAPTKIF18AIDH1 | |
| SCHEMBL2366156 | 0.91 | LMNA (0.36) | TP53LMNAMAPTKIF18AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364975-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-12 | — | — | EP | disclosed |
| EP-2364975-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |