Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TNIK | Q9UKE5 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367333 | 0.84 | TNIK (0.80) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL3397653 | 0.83 | LMNA (0.80) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL3394772 | 0.83 | MAPT (0.64) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL2366826 | 0.82 | TNIK (0.80) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL2366920 | 0.80 | TNIK (0.79) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL3393628 | 0.80 | TNIK (0.74) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL2366092 | 0.80 | TNIK (0.74) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL2367264 | 0.79 | TNIK (0.72) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL3394962 | 0.79 | TNIK (0.72) | LMNATP53POLBMAPTTNIK | |
| SCHEMBL3394616 | 0.77 | TNIK (0.70) | LMNATP53POLBMAPTTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364149-A1 | TNIK INHIBITOR AND THE USE | National Cancer Center (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |