Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.46 |
| ▸ | FLT1 | P17948 | 4/20 | 0.46 |
| ▸ | FLT4 | P35916 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29565760 | 0.99 | KIT (0.52) | KITEHMT2EGFRFGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL19260531 | 0.99 | KIT (0.52) | KITEHMT2EGFRFGFR1FLT1 | |
| SCHEMBL19260534 | 0.83 | KIT (0.54) | KITEHMT2EGFRFGFR1FLT1 | |
| SCHEMBL19260530 | 0.82 | KIT (0.55) | KITEHMT2EGFRFGFR1FLT1 | |
| SCHEMBL19260529 | 0.80 | EHMT2 (0.49) | KITEHMT2EGFR | |
| Trifluoroacetic Acid SCHEMBL20720749 | 0.77 | KIT (0.47) | KITEHMT2EGFRFGFR1FLT1 | |
| SCHEMBL30063343 | 0.76 | EHMT2 (0.61) | EHMT2CHEK1CHEK2 | |
| SCHEMBL24844128 | 0.76 | EHMT2 (0.61) | EHMT2CHEK1CHEK2 | |
| SCHEMBL24843852 | 0.76 | EHMT2 (0.69) | EHMT2CHEK1CHEK2 | |
| Trifluoroacetic Acid SCHEMBL20720740 | 0.75 | KIT (0.49) | KITEHMT2EGFRFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416963-B1 | HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2021-07-28 | — | — | EP | disclosed |