Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671491 | 0.89 | BACE1 (0.64) | BACE1ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL23671499 | 0.88 | BACE1 (0.69) | BACE1ALDH1A1ATML3MBTL1LMNA | |
| SCHEMBL23671503 | 0.85 | BACE1 (0.66) | BACE1ALDH1A1ATML3MBTL1HRH3 | |
| SCHEMBL23671489 | 0.84 | BACE1 (0.58) | BACE1ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL23671493 | 0.84 | BACE1 (0.58) | BACE1ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL21616826 | 0.81 | BACE1 (0.59) | BACE1ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL21616857 | 0.79 | BACE1 (0.62) | BACE1ALDH1A1HRH3KDM4ELMNA | |
| SCHEMBL23671496 | 0.79 | BACE1 (0.53) | BACE1ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL21616859 | 0.77 | BACE1 (1.00) | BACE1HRH3 | |
| SCHEMBL21616841 | 0.74 | BACE1 (0.69) | BACE1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) (FR) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230131-A1 | POLYAMINO BIARYL COMPOUNDS AND THEIR USE | ABCG2, SLC10A1, CYP3A43 | BACE1 1582/4885ALDH1A1 177/4885ATM 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.