Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401595 | 0.91 | MAPT (0.53) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL4850576 | 0.86 | KLK7 (0.50) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL10873871 | 0.82 | KLK7 (0.67) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL1021830 | 0.82 | CTSK (0.50) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL8955505 | 0.82 | KLK7 (0.64) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL1023528 | 0.82 | KLK7 (0.47) | KLK7KLK5MAPTCTSKCTSS | |
| SCHEMBL3820597 | 0.81 | KLK7 (0.50) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL375888 | 0.81 | KLK7 (0.50) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL13120843 | 0.81 | KLK7 (0.63) | KLK7KLK5MAPTCTSKSYK | |
| SCHEMBL14014416 | 0.81 | KLK7 (0.63) | KLK7KLK5MAPTCTSKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |