Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23672207 | 1.00 | EZH2 (0.55) | EZH2ELANE | |
| SCHEMBL30011294 | 0.89 | EZH2 (0.46) | EZH2ELANE | |
| SCHEMBL23672079 | 0.89 | EZH2 (0.47) | EZH2ELANE | |
| SCHEMBL16377040 | 0.89 | ELANE (0.45) | EZH2ELANE | |
| SCHEMBL23682377 | 0.89 | EZH2 (0.47) | EZH2ELANE | |
| SCHEMBL23672082 | 0.89 | EZH2 (0.47) | EZH2ELANE | |
| SCHEMBL23672051 | 0.88 | EZH2 (0.58) | EZH2 | |
| Hydrochloric Acid SCHEMBL23672230 | 0.88 | EZH2 (0.46) | EZH2ELANE | |
| SCHEMBL23672050 | 0.88 | EZH2 (0.58) | EZH2 | |
| Hydrochloric Acid SCHEMBL23672232 | 0.88 | EZH2 (0.46) | EZH2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197194-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 四川海思科制药有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11459315-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| EP-3707136-B1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20210230148-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459315-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | TPMT, TET1, TET2 | EZH2 150/4885ELANE 2487/4885 |
| US-20210230148-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | TPMT, TET1, TET2 | EZH2 150/4885ELANE 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.