Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23672207 | 0.89 | EZH2 (0.55) | EZH2ELANE | |
| SCHEMBL23672208 | 0.89 | EZH2 (0.55) | EZH2ELANE | |
| SCHEMBL28666580 | 0.87 | EZH2 (0.47) | EZH2 | |
| SCHEMBL23682377 | 0.86 | EZH2 (0.47) | EZH2ELANE | |
| SCHEMBL16377040 | 0.86 | ELANE (0.45) | EZH2ELANE | |
| SCHEMBL23672079 | 0.86 | EZH2 (0.47) | EZH2ELANE | |
| SCHEMBL23672082 | 0.86 | EZH2 (0.47) | EZH2ELANE | |
| Hydrochloric Acid SCHEMBL23672230 | 0.85 | EZH2 (0.46) | EZH2ELANE | |
| SCHEMBL23672051 | 0.85 | EZH2 (0.58) | EZH2 | |
| Hydrochloric Acid SCHEMBL23672232 | 0.85 | EZH2 (0.46) | EZH2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197194-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 四川海思科制药有限公司 | 2022-10-18 | — | — | CN | disclosed |