Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 18/20 | 0.81 |
| ▸ | BCL2 | P10415 | 13/20 | 0.71 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367577 | 1.00 | MCL1 (0.81) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL2368020 | 0.88 | MCL1 (0.88) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL2367321 | 0.83 | MCL1 (1.00) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL2367266 | 0.83 | MCL1 (1.00) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL14935302 | 0.83 | MCL1 (1.00) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL14935267 | 0.81 | MCL1 (0.78) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL14935268 | 0.81 | MCL1 (0.78) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL14935296 | 0.80 | MCL1 (0.82) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL13354203 | 0.74 | MCL1 (0.64) | MCL1BCL2BCL2L1FGFR1 | |
| SCHEMBL2367188 | 0.73 | MCL1 (1.00) | MCL1BCL2BCL2L1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251188-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2011-10-13 | — | — | US | disclosed |
| EP-2366701-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | Dalian University Of Technology (CN) | 2011-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251188-A1 | ACENAPHTHO HETEROCYCLE COMPOUNDS, CYCLODEXTRIN INCLUSION COMPOUNDS AND COMPLEXES, AND USES IN THE MANUFACTURES OF BH3 PROTEIN ANALOGUE, BCL-2 FAMILY PROTEIN INHIBITORS THEREOF | BID, BCL2, BAX | MCL1 10/4885BCL2 2/4885BCL2L1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.