Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.67 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.67 |
| ▸ | CCR5 | P51681 | 10/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23683235 | 0.88 | USP28 (0.74) | USP28USP25CCR5SLC6A4PTGER1 | |
| SCHEMBL23683250 | 0.83 | USP28 (0.48) | USP28USP25CCR5SLC6A4PTPN7 | |
| SCHEMBL25810028 | 0.82 | USP28 (0.75) | USP28USP25CCR5MEN1KMT2A | |
| SCHEMBL31464215 | 0.81 | USP28 (1.00) | USP28USP25CCR5MEN1KMT2A | |
| SCHEMBL29841090 | 0.81 | USP28 (1.00) | USP28USP25CCR5MEN1KMT2A | |
| SCHEMBL23683179 | 0.81 | USP28 (1.00) | USP28USP25CCR5MEN1KMT2A | |
| SCHEMBL23683172 | 0.79 | USP28 (0.57) | USP28USP25CCR5PTGER1 | |
| SCHEMBL28602479 | 0.79 | USP28 (0.60) | USP28USP25CCR5SLC6A4PTGER1 | |
| SCHEMBL30038784 | 0.79 | USP28 (0.60) | USP28USP25CCR5SLC6A4PTGER1 | |
| SCHEMBL23673334 | 0.79 | USP28 (0.60) | USP28USP25CCR5SLC6A4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214097-B | Compounds for the treatment of alzheimer's disease | 厦门大学 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021147971-A1 | COMPOUND FOR TREATING ALZHEIMER'S DISEASE | 厦门大学 | 2021-07-29 | — | — | WO | disclosed |
| WO-2021147971-A1 | COMPOUND FOR TREATING ALZHEIMER'S DISEASE | 厦门大学 | 2021-07-29 | — | — | WO | disclosed |