Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919760 | 0.87 | SLC7A5 (0.38) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL977470 | 0.87 | SLC7A5 (0.38) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL10662683 | 0.85 | NOS1 (0.35) | NOS1NOS3NOS2 | |
| SCHEMBL10659347 | 0.85 | NOS1 (0.35) | NOS1NOS3NOS2 | |
| SCHEMBL6361064 | 0.85 | NOS1 (0.43) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL6360497 | 0.85 | NOS1 (0.43) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL29104750 | 0.79 | ELANE (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL6954465 | 0.79 | CYP3A4 (0.37) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL6950879 | 0.79 | CYP3A4 (0.37) | NOS1NOS3NOS2CYP2D6CA1 | |
| SCHEMBL1926084 | 0.79 | CYP3A4 (0.37) | NOS1NOS3NOS2CYP2D6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |