SCHEMBL2367400

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@@H](C)OC(=O)C(F)(F)F)[C@H](C)O

nearest known ligand 0.40

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	3/20	0.40

▸	NPY4R	P50391	2/20	0.38

▸	KEAP1	Q14145	2/20	0.37

▸	VIPR2	P41587	3/20	0.35

▸	VIPR1	P32241	1/20	0.35

▸	KRAS	P01116	4/20	0.35

▸	PTH1R	Q03431	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367032	1.00	RXFP1 (0.40)	RXFP1NPY4RKEAP1VIPR2VIPR1
SCHEMBL2367433	0.96	NPY4R (0.40)	RXFP1NPY4RKEAP1
SCHEMBL2367050	0.95	RXFP1 (0.42)	RXFP1NPY4RVIPR2VIPR1
SCHEMBL2367091	0.94	RXFP1 (0.41)	RXFP1NPY4RKEAP1VIPR2VIPR1
SCHEMBL2366970	0.94	RXFP1 (0.41)	RXFP1NPY4RKEAP1VIPR2VIPR1
SCHEMBL2367328	0.94	RXFP1 (0.41)	RXFP1NPY4RKEAP1VIPR2VIPR1
SCHEMBL3046711	0.93	RXFP1 (0.40)	RXFP1NPY4RKEAP1VIPR2VIPR1
SCHEMBL2368042	0.91	RXFP1 (0.44)	RXFP1NPY4RKEAP1PTH1R
SCHEMBL2366814	0.91	RXFP1 (0.42)	RXFP1NPY4RKEAP1KRASPTH1R
SCHEMBL2367832	0.91	RXFP1 (0.37)	RXFP1NPY4RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed