SCHEMBL2367050

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](C)OC(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	4/20	0.42

▸	NPY4R	P50391	5/20	0.38

▸	SLC2A1	P11166	2/20	0.35

▸	NPY5R	Q15761	3/20	0.35

▸	NPY1R	P25929	3/20	0.35

▸	VIPR1	P32241	2/20	0.35

▸	VIPR2	P41587	2/20	0.35

▸	TFPI	P10646	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367433	0.96	NPY4R (0.40)	RXFP1NPY4RNPY5RNPY1R
SCHEMBL2367032	0.95	RXFP1 (0.40)	RXFP1NPY4RVIPR1VIPR2
SCHEMBL2367400	0.95	RXFP1 (0.40)	RXFP1NPY4RVIPR1VIPR2
SCHEMBL2367390	0.95	RXFP1 (0.38)	RXFP1NPY4R
SCHEMBL2367247	0.95	RXFP1 (0.39)	RXFP1NPY4R
SCHEMBL2367328	0.94	RXFP1 (0.41)	RXFP1NPY4RVIPR1VIPR2TFPI
SCHEMBL2366970	0.94	RXFP1 (0.41)	RXFP1NPY4RVIPR1VIPR2TFPI
SCHEMBL2368042	0.91	RXFP1 (0.44)	RXFP1NPY4RNPY5RNPY1R
SCHEMBL2366814	0.91	RXFP1 (0.42)	RXFP1NPY4RSLC2A1NPY5RNPY1R
SCHEMBL5073480	0.91	NPY4R (0.47)	NPY4RSLC2A1NPY5RNPY1RVIPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed