SCHEMBL2367412

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](N)[C@H](O)C(C)C)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](C)O

nearest known ligand 0.39

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	6/20	0.39

▸	KEAP1	Q14145	1/20	0.35

▸	RXFP4	Q8TDU9	2/20	0.35

▸	RXFP3	Q9NSD7	2/20	0.35

▸	PTH1R	Q03431	1/20	0.34

▸	NPY4R	P50391	1/20	0.34

▸	PRSS1	P07477	1/20	0.34

▸	FURIN	P09958	1/20	0.34

▸	VIPR2	P41587	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367832	0.99	RXFP1 (0.37)	RXFP1KEAP1RXFP4RXFP3NPY4R
SCHEMBL2367091	0.95	RXFP1 (0.41)	RXFP1KEAP1PTH1RNPY4RVIPR2
SCHEMBL2371869	0.95	RXFP1 (0.36)	RXFP1KEAP1RXFP4RXFP3PTH1R
SCHEMBL2368042	0.95	RXFP1 (0.44)	RXFP1KEAP1PTH1RNPY4RPRSS1
SCHEMBL2367458	0.94	RXFP1 (0.35)	RXFP1KEAP1RXFP4RXFP3PTH1R
SCHEMBL2367313	0.93	NPY4R (0.42)	RXFP1KEAP1NPY4RPRSS1FURIN
SCHEMBL2366814	0.92	RXFP1 (0.42)	RXFP1KEAP1PTH1RNPY4RPRSS1
SCHEMBL2367128	0.91	NPY4R (0.41)	RXFP1KEAP1PTH1RNPY4RVIPR2
SCHEMBL3046711	0.91	RXFP1 (0.40)	RXFP1KEAP1RXFP4RXFP3PTH1R
SCHEMBL2367191	0.90	NPY4R (0.43)	KEAP1NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed