Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | RAMP3 | O60896 | 4/20 | 0.37 |
| ▸ | CALCR | P30988 | 4/20 | 0.37 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367191 | 0.98 | NPY4R (0.43) | NPY4RKEAP1NPY1RNPY2RNPY5R | |
| SCHEMBL2367091 | 0.95 | RXFP1 (0.41) | NPY4RKEAP1RXFP1NPY1RNPY2R | |
| SCHEMBL2368042 | 0.94 | RXFP1 (0.44) | NPY4RKEAP1FURINPRSS1RXFP1 | |
| SCHEMBL2372530 | 0.94 | NPY4R (0.40) | NPY4RKEAP1NPY1RNPY2RNPY5R | |
| SCHEMBL2367412 | 0.93 | RXFP1 (0.39) | NPY4RKEAP1FURINPRSS1RXFP1 | |
| SCHEMBL2366814 | 0.91 | RXFP1 (0.42) | NPY4RKEAP1FURINPRSS1RXFP1 | |
| SCHEMBL2367832 | 0.91 | RXFP1 (0.37) | NPY4RKEAP1RXFP1 | |
| SCHEMBL2373308 | 0.91 | NPY4R (0.50) | NPY4RKEAP1NPY1RNPY2RNPY5R | |
| SCHEMBL2367128 | 0.90 | NPY4R (0.41) | NPY4RKEAP1RXFP1NPY1RNPY2R | |
| SCHEMBL3046711 | 0.90 | RXFP1 (0.40) | NPY4RKEAP1RXFP1NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |