⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23689691 | 0.72 | — | — | |
| SCHEMBL22380665 | 0.71 | — | — | |
| SCHEMBL19344897 | 0.68 | — | — | |
| SCHEMBL19344901 | 0.68 | ADRA2A (0.30) | — | |
| SCHEMBL32686473 | 0.66 | — | — | |
| SCHEMBL21293547 | 0.64 | — | — | |
| SCHEMBL32686538 | 0.61 | — | — | |
| SCHEMBL10531111 | 0.59 | — | — | |
| SCHEMBL23705835 | 0.55 | — | — | |
| SCHEMBL23706250 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230108442-A1 | NOVEL ANTIMALARIAL AGENT CONTAINING HETEROCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-04-06 | — | — | US | disclosed |
| US-20230108442-A1 | NOVEL ANTIMALARIAL AGENT CONTAINING HETEROCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-04-06 | — | — | US | disclosed |
| EP-4058147-A1 | NOVEL ANTIMALARIAL AGENT CONTAINING HETEROCYCLIC COMPOUND | Eisai R&D Management Co., Ltd (JP) | 2022-09-21 | — | — | EP | disclosed |
| CN-114829351-A | Novel antimalarial agents containing heterocyclic compounds | 卫材R&D管理有限公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021149692-A1 | NOVEL ANTIMALARIAL AGENT CONTAINING HETEROCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021149692-A1 | NOVEL ANTIMALARIAL AGENT CONTAINING HETEROCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-07-29 | — | — | WO | disclosed |