SCHEMBL236748

SCHEMBL236748

OCCOc1cccc(Br)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
RECQL P46063 1/20 0.57
MAOB P27338 7/20 0.56
KDM4E B2RXH2 5/20 0.55
LMNA P02545 1/20 0.55
RAB9A P51151 2/20 0.54
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.53
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30693705 0.90 ALDH1A1 (0.55) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL6989572 0.90 ALDH1A1 (0.55) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL22491455 0.89 MAOB (0.53) ALDH1A1RECQLMAOBKDM4ELMNA
SCHEMBL5922423 0.89 ALDH1A1 (0.57) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL10876065 0.88 ALDH1A1 (0.53) ALDH1A1RECQLMAOBKDM4ELMNA
SCHEMBL13883739 0.87 MAOB (0.64) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL7162438 0.85 MAOB (0.62) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL48418 0.85 ALDH1A1 (0.70) ALDH1A1RECQLKMT2AGAA
SCHEMBL14359006 0.85 MAOB (0.53) ALDH1A1MAOBKDM4ELMNARAB9A
SCHEMBL900772 0.84 MAOB (0.56) ALDH1A1MAOBKDM4ELMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety CURIS INC (US) 2025-07-17 US disclosed
US-12195490-B2 STRAD-binding agents and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-14 US disclosed
US-20230227467-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY CURIS INC (US) 2023-07-20 US disclosed
US-20230192689-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2023-06-22 US disclosed
US-20230192689-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2023-06-22 US disclosed
US-20230192689-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2023-06-22 US disclosed
CN-115916966-A STRAD binding agents and uses thereof 加利福尼亚大学董事会 2023-04-04 CN disclosed
US-11608337-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2023-03-21 US disclosed
US-11597732-B2 Phosphoinositide 3-kinase inhibitors with a zinc binding moiety CURIS, INC. (US) 2023-03-07 US disclosed
US-20230040299-A1 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2023-02-09 US disclosed
EP-1349852-A2 4-(HETERO)ARYL SUBSTITUTED INDOLINONES Sugen, Inc. (US) 2003-10-08 EP disclosed
US-20030176528-A1 Photosensitive resin composition, dry film, and workpiece using the same MITSUI CHEMICALS, INC. (JP) 2003-09-18 US disclosed
US-20030069297-A1 4-aryl substituted indolinones SUGEN, INC. 2003-04-10 US disclosed
US-6495568-B1 TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES WARNER-LAMBERT COMPANY 2002-12-17 US disclosed
US-6476258-B1 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-05 US disclosed
WO-2002055517-A2 4-(HETERO)ARYL SUBSTITUTED INDOLINONES CUI JINGRONG (US) 2002-07-18 WO disclosed
EP-1099692-A1 N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES Eisai Co., Ltd. (JP) 2001-05-16 EP disclosed
EP-1067108-A2 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed
EP-1036062-A1 HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS Pfizer Limited (GB) 2000-09-20 EP disclosed
WO-1999029667-A1 HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS PFIZER LIMITED (GB) 1999-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192689-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS CD74, IL2, ICOS ALDH1A1 223/4885RECQL 1238/4885MAOB 650/4885
US-20030069297-A1 4-aryl substituted indolinones CDK5, CAMK4, TNK2 ALDH1A1 1671/4885RECQL 3241/4885MAOB 1182/4885
US-11597732-B2 Phosphoinositide 3-kinase inhibitors with a zinc binding moiety BAZ2A, BAZ2B, PI4KB ALDH1A1 3440/4885RECQL 3168/4885MAOB 2139/4885
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety BAZ2A, BAZ2B, PI4KB ALDH1A1 3415/4885RECQL 3194/4885MAOB 2124/4885
US-20230227467-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY BAZ2A, BAZ2B, PI4KB ALDH1A1 3415/4885RECQL 3194/4885MAOB 2124/4885
US-20230040299-A1 2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS BRD4, BRD3, BRD2 ALDH1A1 2706/4885RECQL 1153/4885MAOB 2245/4885
US-12195490-B2 STRAD-binding agents and uses thereof STRAP, STRA6, PLAUR ALDH1A1 3678/4885RECQL 1597/4885MAOB 1610/4885
US-11608337-B2 Heterocyclic compounds as immunomodulators CD74, IL2, ICOS ALDH1A1 223/4885RECQL 1238/4885MAOB 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.