Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100470 | 1.00 | MAPT (0.54) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL26098679 | 0.81 | MAPT (0.65) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL30100479 | 0.78 | GAA (0.55) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL23675450 | 0.75 | MAPT (0.66) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL16645385 | 0.75 | MEN1 (0.61) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL29936212 | 0.75 | MAPT (0.73) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL4263591 | 0.75 | MAPT (0.73) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL6811631 | 0.74 | MAPT (0.67) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL3238215 | 0.72 | KMT2A (0.71) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL11448823 | 0.71 | MAPT (0.68) | MAPTKMT2AALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |