Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | PKM | P14618 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15367493 | 0.85 | MAPT (0.56) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL19327734 | 0.85 | MAPT (0.59) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL10848159 | 0.84 | CA12 (0.64) | MEN1KMT2AMAPTGAACA12 | |
| SCHEMBL16645384 | 0.78 | CA1 (0.52) | MEN1KMT2AMAPTGAACA12 | |
| SCHEMBL16641985 | 0.77 | KMT2A (0.54) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL23675367 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL30100470 | 0.75 | MAPT (0.54) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL4263591 | 0.74 | MAPT (0.73) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL29936212 | 0.74 | MAPT (0.73) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL6815029 | 0.74 | KMT2A (0.70) | MEN1KMT2AMAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105324-A1 | COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES | GRIN2A, GRIN1, GRIN2C | MEN1 4328/4885KMT2A 1058/4885MAPT 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.