Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891560 | 0.87 | PTGER4 (0.56) | POLBMAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL6206188 | 0.81 | PTGER4 (0.58) | PTGER1PTGER4PTGER3PTGER2CYP2C19 | |
| SCHEMBL29141195 | 0.80 | POLB (0.49) | POLBMAPK1TSHRALDH1A1CES2 | |
| SCHEMBL6188684 | 0.79 | FFAR1 (0.50) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL9194437 | 0.79 | DPP4 (0.58) | POLBMAPK1ALDH1A1CES1MAPT | |
| SCHEMBL19616161 | 0.78 | PTGDR2 (0.46) | POLBMAPK1PRKCZCES2CES1 | |
| SCHEMBL5827236 | 0.77 | ALDH1A1 (0.47) | POLBMAPK1TSHRALDH1A1CES1 | |
| SCHEMBL29383344 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1SMN1; SMN2MAPTCYP2C19 | |
| SCHEMBL151684 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1SMN1; SMN2MAPTCYP2C19 | |
| SCHEMBL11994149 | 0.77 | MAPT (0.44) | TSHRALDH1A1MAPTHTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |