Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.66 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.66 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.56 |
| ▸ | SCN2B | O60939 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 1/20 | 0.56 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388956 | 0.87 | SCN9A (0.77) | SCN9ASCN5ASCN7A | |
| SCHEMBL19427315 | 0.81 | SCN9A (0.84) | SCN9ASCN5ASCN7ASCN2BSCN1A | |
| SCHEMBL19388930 | 0.81 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL15536384 | 0.80 | SCN9A (1.00) | SCN9ASCN5ASCN7ASCN2BSCN1A | |
| SCHEMBL20697611 | 0.78 | SCN9A (0.51) | SCN9ASCN5ASCN7A | |
| SCHEMBL20697710 | 0.77 | SCN9A (0.48) | SCN9ASCN5ASCN7ASCN2BSCN1A | |
| SCHEMBL20697829 | 0.76 | SCN9A (0.52) | SCN9ASCN5ASCN7A | |
| SCHEMBL19388900 | 0.76 | SCN9A (0.51) | SCN9ASCN5ASCN7A | |
| SCHEMBL15536764 | 0.75 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL19084140 | 0.74 | SCN9A (0.46) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854782-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |