Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878732 | 0.90 | SYK (0.65) | SYKIDO1LTA4HCTSSPPARA | |
| SCHEMBL29879918 | 0.90 | SYK (0.65) | SYKIDO1LTA4HCTSSPPARA | |
| SCHEMBL1021939 | 0.86 | MAPT (0.52) | SYKIDO1LTA4HMAPTSLC1A3 | |
| SCHEMBL918814 | 0.86 | MAPT (0.52) | SYKIDO1LTA4HMAPTSLC1A3 | |
| SCHEMBL7295558 | 0.85 | MAPT (0.56) | SYKIDO1MAPTSLC1A3SLC1A1 | |
| SCHEMBL3824366 | 0.85 | MAPT (0.56) | SYKIDO1MAPTSLC1A3SLC1A1 | |
| SCHEMBL6500075 | 0.85 | SYK (0.61) | SYKLTA4HCTSSMAPTSLC1A3 | |
| SCHEMBL7438565 | 0.81 | SLC1A3 (0.41) | SLC1A3SLC1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1627707 | 0.80 | SYK (0.67) | SYKIDO1CTSSPPARAMAPT | |
| SCHEMBL1627709 | 0.80 | SYK (0.61) | SYKIDO1LTA4HCTSSPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |