Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367757 | 0.81 | SYK (0.60) | SLC1A3SLC1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19331556 | 0.80 | ALDH1A1 (0.47) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL15670464 | 0.77 | SLC1A3 (0.40) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL20263694 | 0.77 | SLC1A3 (0.51) | SLC1A3SLC1A1KMT2AMEN1LMNA | |
| SCHEMBL7272552 | 0.77 | ALDH1A1 (0.47) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL383649 | 0.77 | ALDH1A1 (0.47) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL3985411 | 0.77 | SLC7A5 (0.56) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL11140649 | 0.76 | ALDH1A1 (0.44) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL27794910 | 0.76 | ALDH1A1 (0.50) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL382326 | 0.76 | ALDH1A1 (0.46) | SLC1A3SLC1A1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492369-B1 | Novel amino and nitro containing tricyclic compounds useful as inhibitors of ace | MERRELL PHARMA INC (US) | 1997-09-17 | — | — | EP | disclosed |