Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 5/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 5/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395829 | 1.00 | TACR1 (0.61) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL18396335 | 1.00 | TACR1 (0.61) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL18395551 | 0.91 | IDO1 (0.54) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL18395822 | 0.91 | CTSL (0.64) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL23677892 | 0.91 | CTSL (0.64) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL24445577 | 0.91 | CTSL (0.64) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL18396309 | 0.91 | CTSL (0.64) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL24445467 | 0.90 | CTSL (0.59) | TACR1CTSLCTSSCTSKMAPT | |
| SCHEMBL23677827 | 0.87 | IDO1 (0.51) | TACR1CTSLCTSSCTSKSCN9A | |
| SCHEMBL18407265 | 0.87 | IDO1 (0.51) | TACR1CTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613420-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-3324958-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2021-07-28 | — | — | EP | disclosed |