SCHEMBL236780

SCHEMBL236780

O=[C]Cc1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1308353 0.82
SCHEMBL263484 0.79 ALOX15 (0.40)
SCHEMBL301421 0.78
SCHEMBL9331253 0.77
SCHEMBL4588023 0.77
SCHEMBL3073342 0.77
SCHEMBL2649139 0.77
Hydrochloric Acid SCHEMBL28986368 0.76
Iodide SCHEMBL28874069 0.76
SCHEMBL28666100 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116322645-A Liquid formulations of long acting conjugates of GLP-2 韩美药品株式会社 2023-06-23 CN claimed
CN-108026143-B Method for preparing physiologically active polypeptide conjugate 韩美药品株式会社 2022-05-27 CN claimed
CN-110269930-A The liquid preparation of protamine zine insulin and insulinoptropic peptides 韩美药品株式会社 2019-09-24 CN claimed
CN-108026143-A Process for preparing physiologically active polypeptide conjugate 韩美药品株式会社 2018-05-11 CN claimed
CN-102112493-B A polypeptide complex comprising non-peptidyl polymer having three functional ends HANMI PHARMACEUTICAL CO LTD 2015-04-01 CN claimed
EP-2643000-A2 THERAPEUTIC PIPERAZINES Dart Neuroscience (Cayman) Ltd (KY) 2013-10-02 EP claimed
WO-2012040258-A2 THERAPEUTIC PIPERAZINES HELICON THERAPEUTICS, INC. (US) 2012-03-29 WO claimed
US-20110065691-A1 THERAPEUTIC PIPERAZINES DART NEUROSCIENCE (CAYMAN) LTD. (KY) 2011-03-17 US claimed
EP-1246836-A2 PEPTIDES FOR TREATMENT OF ERECTILE DYSFUNCTION Ardana Bioscience Limited (GB) 2002-10-09 EP claimed
EP-1142867-A2 Cell adhesion inhibitors BIOGEN, INC. (US) 2001-10-10 EP claimed
WO-1998022610-A1 NOVEL POLYMERIC COMPLEXES FOR THE TRANSFECTION OF NUCLEIC ACIDS, WITH RESIDUES CAUSING THE DESTABILISATION OF CELL MEMBRANES I.D.M. IMMUNO-DESIGNED MOLECULES (FR) 1998-05-28 WO claimed
EP-0752860-A4 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS INC (US) 1998-05-06 EP claimed
EP-0752860-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1997-01-15 EP claimed
US-5574016-A Peptide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-12 US claimed
US-5512588-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-04-30 US claimed
WO-1995021617-A1 ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR COCENSYS, INC. (US) 1995-08-17 WO claimed
EP-0315367-B1 Polypeptides ICI PLC (GB) 1994-04-06 EP claimed
WO-1993002689-A1 SYNTHETIC RIBONUCLEASES AND METHODS FOR PREPARING AND USING SAME UNIVERSITY OF MEDICINE & DENTISTRY (US) 1993-02-18 WO claimed
US-5068222-A Polypeptides for treatment of cancer IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-11-26 US claimed
EP-0315367-A2 Polypeptides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-10 EP claimed