Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23678469 | 0.88 | SCN9A (0.41) | SCN9APNMTAKR1C3AKR1C2AKR1C4 | |
| SCHEMBL23678326 | 0.85 | AGXT (0.43) | PNMT | |
| SCHEMBL23678327 | 0.85 | AGXT (0.43) | PNMT | |
| SCHEMBL23678375 | 0.85 | AGXT (0.43) | PNMT | |
| SCHEMBL23678497 | 0.84 | SCN9A (0.44) | CYP2C9SCN9APRMT5WDR77CTSA | |
| SCHEMBL23678410 | 0.75 | CTSA (0.41) | SCN9APRMT5WDR77CTSA | |
| SCHEMBL23678432 | 0.75 | F9 (0.47) | SCN9ACTSAFAAH | |
| SCHEMBL23678442 | 0.75 | AGXT (0.40) | CTSA | |
| SCHEMBL23678237 | 0.74 | L3MBTL1 (0.33) | CTSA | |
| SCHEMBL23678340 | 0.73 | CTSA (0.38) | CTSAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854788-A1 | COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |