Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 11/20 | 0.47 |
| ▸ | HINT1 | P49773 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352197 | 0.90 | NT5E (0.58) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL22056008 | 0.89 | FUT5 (0.54) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL18158965 | 0.85 | NT5E (0.51) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL22524067 | 0.85 | POLB (0.64) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL21896070 | 0.83 | POLB (0.56) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL16221580 | 0.83 | POLB (0.56) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL23679527 | 0.83 | POLB (0.56) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL21417333 | 0.83 | POLB (0.56) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL16221582 | 0.83 | POLB (0.56) | NT5EPOLBTGM2FUT5HPRT1 | |
| SCHEMBL27275154 | 0.83 | POLB (0.50) | NT5EPOLBTGM2FUT5HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |