Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 15/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790691 | 0.92 | CYP11B2 (0.54) | CYP11B2CYP11B1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18791006 | 0.76 | CYP11B2 (0.42) | CYP11B2CYP11B1ALDH1A1MEN1MAPT | |
| SCHEMBL22236812 | 0.70 | CYP11B2 (0.51) | CYP11B2CYP11B1TLR9TLR8TLR7 | |
| SCHEMBL18791093 | 0.69 | CYP11B2 (0.66) | CYP11B2CYP11B1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18790700 | 0.69 | CYP11B2 (0.56) | CYP11B2CYP11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL23679948 | 0.68 | CYP11B2 (0.53) | CYP11B2CYP11B1TLR9TLR8TLR7 | |
| SCHEMBL18790969 | 0.67 | CYP11B2 (0.52) | CYP11B2CYP11B1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18790702 | 0.67 | CYP11B2 (0.52) | CYP11B2CYP11B1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18791021 | 0.67 | CYP11B2 (0.69) | CYP11B2CYP11B1ALDH1A1MAPTKDM4E | |
| SCHEMBL20340176 | 0.64 | CYP11B2 (0.77) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |