Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718792 | 1.00 | OPRL1 (0.38) | OPRL1OPRK1AKT1OPRD1ALDH1A1 | |
| SCHEMBL23718564 | 0.97 | OPRL1 (0.40) | OPRL1OPRK1AKT1OPRD1 | |
| SCHEMBL24037651 | 0.93 | OPRL1 (0.37) | OPRL1OPRK1AKT1OPRD1ALDH1A1 | |
| SCHEMBL24342133 | 0.91 | OPRL1 (0.38) | OPRL1OPRK1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24037983 | 0.90 | OPRL1 (0.39) | OPRL1OPRK1AKT1OPRD1ALDH1A1 | |
| SCHEMBL23718711 | 0.88 | OPRL1 (0.39) | OPRL1OPRK1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25533497 | 0.87 | FOLH1 (0.35) | OPRL1OPRK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24038011 | 0.87 | OPRL1 (0.39) | OPRL1OPRK1AKT1OPRD1ALDH1A1 | |
| SCHEMBL26067120 | 0.87 | OPRL1 (0.41) | OPRL1OPRK1AKT1OPRD1ALDH1A1 | |
| SCHEMBL24038006 | 0.86 | OPRL1 (0.39) | OPRL1OPRK1AKT1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129345-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |
| EP-3854816-A1 | ANTI-B7H3 ANTIBODY-EXATECAN ANALOG CONJUGATE AND MEDICINAL USE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |