Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680209 | 0.97 | OPRL1 (0.38) | OPRL1OPRK1AKT1OPRD1 | |
| SCHEMBL23718792 | 0.97 | OPRL1 (0.38) | OPRL1OPRK1AKT1OPRD1 | |
| SCHEMBL24037983 | 0.93 | OPRL1 (0.39) | OPRL1OPRK1AKT1FOLH1OPRD1 | |
| SCHEMBL23718711 | 0.91 | OPRL1 (0.39) | OPRL1OPRK1MMP1MMP2MMP3 | |
| SCHEMBL24037651 | 0.90 | OPRL1 (0.37) | OPRL1OPRK1AKT1PSMB1PSMB5 | |
| SCHEMBL24342133 | 0.88 | OPRL1 (0.38) | OPRL1OPRK1MMP1MMP2MMP3 | |
| SCHEMBL24037971 | 0.86 | OPRL1 (0.40) | OPRL1OPRK1AKT1FOLH1HDAC3 | |
| SCHEMBL24038011 | 0.85 | OPRL1 (0.39) | OPRL1OPRK1AKT1FOLH1OPRD1 | |
| SCHEMBL26067120 | 0.85 | OPRL1 (0.41) | OPRL1OPRK1AKT1OPRD1 | |
| SCHEMBL24037979 | 0.85 | OPRL1 (0.39) | OPRL1OPRK1AKT1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129345-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |
| EP-3858386-A1 | LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |