Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.56 |
| ▸ | TDO2 | P48775 | 8/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23707445 | 0.91 | IDO1 (0.57) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL17740948 | 0.86 | IDO1 (0.64) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23707515 | 0.82 | IDO1 (0.45) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23699077 | 0.81 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL30444764 | 0.81 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL30444492 | 0.81 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23707513 | 0.81 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23707447 | 0.79 | IDO1 (0.55) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23707494 | 0.79 | CCNT1 (0.49) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL23680441 | 0.78 | IDO1 (0.61) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854394-A1 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |