Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | FASN | P49327 | 10/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680590 | 0.88 | HPGD (0.52) | HPGDFASN | |
| SCHEMBL23680832 | 0.86 | HPGD (0.53) | HPGD | |
| SCHEMBL23675168 | 0.84 | HPGD (0.48) | HPGDFASNIRAK4 | |
| SCHEMBL29565746 | 0.84 | HPGD (0.58) | HPGD | |
| SCHEMBL23675243 | 0.84 | HPGD (0.58) | HPGD | |
| SCHEMBL29564765 | 0.84 | HPGD (0.48) | HPGDFASNIRAK4 | |
| SCHEMBL25342958 | 0.83 | FASN (0.44) | FASNIRAK4 | |
| SCHEMBL30482656 | 0.83 | FASN (0.44) | FASNIRAK4 | |
| SCHEMBL24463761 | 0.83 | HPGD (0.50) | HPGDFASN | |
| SCHEMBL28887329 | 0.83 | HPGD (0.55) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345702-B1 | PGDH inhibitors and methods of making and using | MYOFORTE THERAPEUTICS, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| WO-2021151014-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345702-B1 | PGDH inhibitors and methods of making and using | HPGD, HPGDS, PTGS1 | HPGD 1/4885FASN 214/4885IRAK4 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.