⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862139 | 0.64 | — | — | |
| SCHEMBL706367 | 0.64 | — | — | |
| SCHEMBL1051690 | 0.61 | — | — | |
| SCHEMBL3419407 | 0.61 | — | — | |
| SCHEMBL11669343 | 0.59 | — | — | |
| SCHEMBL4543876 | 0.58 | ALDH1A1 (0.36) | — | |
| SCHEMBL837171 | 0.57 | — | — | |
| SCHEMBL4272328 | 0.57 | — | — | |
| SCHEMBL996896 | 0.56 | — | — | |
| SCHEMBL15926088 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403296-B1 | MONOMERS, POLYMERS, AND OPHTHALMIC LENSES AND CONTACT LENSES MADE BY USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2008-05-21 | — | — | EP | claimed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |
| EP-0184692-B1 | METHOD OF PREPARATION OF O-SILYLATED KETENE ACETALS AND ENOL ETHERS | UNION CARBIDE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0228095-A2 | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |