Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 9/20 | 0.35 |
| ▸ | NPY1R | P25929 | 7/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21323139 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL21137521 | 0.82 | DPP4 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL29233240 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL19450715 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL20385917 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL23394645 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL21233231 | 0.81 | DPP4 (0.40) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL22797764 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL20795868 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP9DPP7NPY4R | |
| SCHEMBL22848364 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP9DPP7NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177885-A1 | ENDOSOMAL CLEAVABLE LINKERS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-06-09 | — | — | US | disclosed |
| WO-2021151031-A1 | PROTEIN-ANTIVIRAL COMPOUND CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |