Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845545 | 0.78 | CDK2 (0.47) | CDK2CDK1CDK3GAAGFER | |
| SCHEMBL25484148 | 0.75 | CDK2 (0.45) | CDK2CDK1CDK3GAAGFER | |
| SCHEMBL23815752 | 0.74 | GAA (0.44) | CDK2CDK1CDK3GAAGFER | |
| SCHEMBL23815871 | 0.66 | GAA (0.43) | CDK2CDK1CDK3GAAALDH1A1 | |
| SCHEMBL9965751 | 0.64 | — | — | |
| SCHEMBL25696684 | 0.62 | ALDH1A1 (0.54) | CDK2GAAGFERALDH1A1L3MBTL1 | |
| SCHEMBL27331156 | 0.62 | PIK3CG (0.46) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28195542 | 0.62 | GAA (0.40) | CDK2CDK1CDK3GAAALDH1A1 | |
| SCHEMBL4395319 | 0.61 | ALDH1A1 (0.66) | CDK2GAAGFERALDH1A1L3MBTL1 | |
| SCHEMBL20679921 | 0.60 | MEN1 (0.40) | CDK2GAAALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | ZFX, F13B, GRN | CDK2 1981/4885CDK1 2325/4885CDK3 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.