Chlorocresol

Chlorocresol

SCHEMBL2368412

Cc1cc(O)ccc1Cl.Oc1ccccc1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
ALOX15 P16050 3/20 0.48
CYP3A4 P08684 2/20 0.48
CHRM1 P11229 1/20 0.48
MAOA P21397 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
HTR2B P41595 1/20 0.48
ESR2 Q92731 6/20 0.47
ESR1 P03372 5/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA12 O43570 2/20 0.43
CA2 P00918 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA1 P00915 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
MAPT P10636 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorocresol SCHEMBL6552674 0.89 HSD17B10 (0.59) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL12344 0.89
Chlorocresol SCHEMBL29377724 0.89
Chlorocresol SCHEMBL8736464 0.88 ESR2 (0.52) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL9396313 0.87 HSD17B10 (0.56) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL28185631 0.87 HSD17B10 (0.56) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL29353909 0.87 HSD17B10 (0.56) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL1712039 0.87 HSD17B10 (0.56) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL1712038 0.87 HSD17B10 (0.56) HSD17B10ALOX15CYP3A4CHRM1MAOA
Chlorocresol SCHEMBL1413345 0.85 TRPA1 (0.45) HSD17B10ALOX15CYP3A4CHRM1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210283259-A1 PROTEIN FORMULATIONS ARECOR LTD (GB) 2021-09-16 US claimed
US-20130149335-A1 PROTEIN FORMULATIONS ARECOR LIMITED 2013-06-13 US claimed
EP-2538974-A1 PROTEIN FORMULATIONS Arecor Limited (GB) 2013-01-02 EP claimed
WO-2011104557-A1 PROTEIN FORMULATIONS ARECOR LIMITED (GB) 2011-09-01 WO claimed
US-5063134-A Silicon-containing novolaks for multilayer photoresists developed by an aqueous alkaline solution; oxygen-plasma resistance; resolution KABUSHIKI KAISHA TOSHIBA (JP) 1991-11-05 US disclosed