SCHEMBL23685138

SCHEMBL23685138

O=C(NC[C@H](c1cc2c(c(-c3ccc(F)cc3)n1)OC[C@H]2C(F)(F)F)C1COC1)c1cc(OC2CC2)c2ncccc2c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.34
HRH1 P35367 1/20 0.31
KCNH2 Q12809 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23685128 0.96 AR (0.35) ARHRH1KCNH2POLB
SCHEMBL23683774 0.90 AR (0.34) ARHRH1KCNH2POLB
SCHEMBL23685131 0.90 AR (0.35) ARHRH1KCNH2POLB
SCHEMBL23685206 0.90 AR (0.35) ARHRH1KCNH2POLB
SCHEMBL23685207 0.86 SLC5A7 (0.38)
SCHEMBL23685130 0.86 SLC5A7 (0.38)
SCHEMBL23685221 0.84 SLC5A7 (0.35)
SCHEMBL23683750 0.83 AR (0.30) AR
SCHEMBL23683773 0.83 AR (0.35) ARHRH1KCNH2POLB
SCHEMBL23905701 0.83 AR (0.35) ARHRH1KCNH2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021150806-A1 HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2021-07-29 WO disclosed