Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 16/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905426 | 0.94 | AR (0.34) | ARHRH1KCNH2POLB | |
| SCHEMBL24363611 | 0.93 | POLB (0.38) | POLBHTR2CHTR2B | |
| SCHEMBL24345454 | 0.93 | POLB (0.38) | POLBHTR2CHTR2B | |
| SCHEMBL23905558 | 0.90 | GABRA5 (0.31) | AR | |
| SCHEMBL23905459 | 0.87 | POLB (0.36) | POLB | |
| SCHEMBL24363581 | 0.86 | SLC5A7 (0.38) | — | |
| SCHEMBL23683774 | 0.84 | AR (0.34) | ARHRH1KCNH2POLBCYP3A4 | |
| SCHEMBL24345695 | 0.84 | AR (0.35) | ARHRH1KCNH2POLBCYP3A4 | |
| SCHEMBL24987227 | 0.84 | AR (0.36) | ARHRH1KCNH2POLBCYP3A4 | |
| SCHEMBL23685131 | 0.84 | AR (0.35) | ARHRH1KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |