Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717366 | 0.93 | ENPP2 (0.32) | GABRA5 | |
| SCHEMBL23717045 | 0.90 | POLB (0.37) | CFTRGABRA5POLBKMT2A | |
| SCHEMBL23717324 | 0.87 | CFTR (0.31) | CFTRGABRA5 | |
| SCHEMBL24345713 | 0.87 | CFTR (0.31) | CFTRGABRA5 | |
| SCHEMBL23717101 | 0.87 | CFTR (0.34) | CFTR | |
| SCHEMBL23685126 | 0.85 | ENPP2 (0.32) | — | |
| SCHEMBL23717502 | 0.83 | AR (0.35) | POLB | |
| SCHEMBL24363729 | 0.82 | POLB (0.38) | CFTRPOLBKMT2A | |
| SCHEMBL24345444 | 0.81 | CSNK1D (0.34) | — | |
| SCHEMBL23683778 | 0.81 | POLB (0.38) | CFTRGABRA5POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150806-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |