Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257328 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| SCHEMBL25949959 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| SCHEMBL5908926 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| SCHEMBL5712005 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| SCHEMBL23842922 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| SCHEMBL29008423 | 1.00 | SHBG (0.56) | SHBGEPHX1DPP4TP53KDM4E | |
| Hydrochloric Acid SCHEMBL6848858 | 0.97 | SHBG (0.54) | SHBGEPHX1DPP4TP53KDM4E | |
| Hydrochloric Acid SCHEMBL20302411 | 0.97 | SHBG (0.54) | SHBGEPHX1DPP4TP53KDM4E | |
| Ammonia Solution, Strong SCHEMBL1560591 | 0.97 | SHBG (0.54) | SHBGEPHX1DPP4TP53KDM4E | |
| Hydrochloric Acid SCHEMBL1356288 | 0.97 | SHBG (0.54) | SHBGEPHX1DPP4TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230697-A1 | GENOME-WIDE CLASSIFIERS FOR DETECTION OF SUBACUTE TRANSPLANT REJECTION AND OTHER TRANSPLANT CONDITIONS | THE SCRIPPS RESEARCH INSTITUTE | 2021-07-29 | — | — | US | disclosed |