Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368731 | 1.00 | FFAR1 (0.59) | FFAR1FFAR4GRIK1GRIK2GPR84 | |
| SCHEMBL2368732 | 1.00 | FFAR1 (0.59) | FFAR1FFAR4GRIK1GRIK2GPR84 | |
| SCHEMBL3524848 | 0.94 | FFAR1 (0.61) | FFAR1FFAR4GRIK1GRIK2GPR84 | |
| Glutamic Acid SCHEMBL1395888 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GRIK1GRIK2GPR84 | |
| SCHEMBL23531056 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL1738925 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL1527353 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL5048329 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL3689310 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 | |
| SCHEMBL660684 | 0.86 | GRIK1 (0.69) | FFAR1GRIK1GRIK2GPR84SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013015-B2 | Small molecule inhibitors of ghrelin O-acyltransferase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-09-06 | — | — | US | disclosed |