⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270059 | 1.00 | — | — | |
| SCHEMBL14270063 | 1.00 | — | — | |
| SCHEMBL14720997 | 0.95 | TSHR (0.43) | — | |
| SCHEMBL13894451 | 0.93 | TSHR (0.41) | — | |
| SCHEMBL24616619 | 0.84 | — | — | |
| SCHEMBL12055705 | 0.84 | — | — | |
| SCHEMBL10210041 | 0.84 | — | — | |
| SCHEMBL2666633 | 0.84 | — | — | |
| SCHEMBL2561936 | 0.84 | — | — | |
| SCHEMBL14270060 | 0.81 | DPP4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652164-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024233812-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4423069-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023077046-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-115427421-A | 3' -ketoside compounds with slow release of volatile alcohols | 格莱克科学有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-9951431-B2 | Electrocatalytic hydrogenation and hydrodeoxygenation of oxygenated and unsaturated organic compounds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| CN-105764888-B | A kind of new 3 azabicyclos [3.1.0] hexame derivatives and its medical usage | 株式会社三和化学研究所 | 2018-04-06 | — | — | CN | disclosed |
| CN-107089898-A | A kind of method of biomass phenolic compound catalytic hydrogenation synthesizing cyclohexane 1 alcohols compound | 浙江工业大学 | 2017-08-25 | — | — | CN | disclosed |
| US-9718825-B2 | N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals | SANOFI (FR) | 2017-08-01 | — | — | US | disclosed |
| EP-2970259-B1 | N-(4-(AZAINDAZOL-6-YL)-PHENYL)-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2016-12-21 | — | — | EP | disclosed |
| EP-1366026-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040077669-A1 | Pyrimidine compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1366026-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002024663-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-28 | — | — | WO | disclosed |
| EP-0219257-B1 | Esters of dihydrolysergic acid | LILLY CO ELI (US) | 1994-03-09 | — | — | EP | disclosed |
| US-4968802-A | ESTERIFICATION WITH ALKOXYCYCLOALKYL SULFONATE | ELI LILLY AND COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4914100-A | TREATING THROMBOSIS | ELI LILLY AND COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4847261-A | ANALGESICS, HYPOTENSIVES | ELI LILLY AND COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4714704-A | Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT receptor antagonists | ELI LILLY AND COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0219257-A2 | Esters of dihydrolysergic acid | ELI LILLY AND COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |