⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666633 | 1.00 | — | — | |
| SCHEMBL12055705 | 1.00 | — | — | |
| SCHEMBL10210041 | 1.00 | — | — | |
| SCHEMBL2561936 | 1.00 | — | — | |
| SCHEMBL7592602 | 0.87 | — | — | |
| SCHEMBL2369042 | 0.84 | — | — | |
| SCHEMBL14270063 | 0.84 | — | — | |
| SCHEMBL14720997 | 0.84 | TSHR (0.43) | — | |
| SCHEMBL14270059 | 0.84 | — | — | |
| SCHEMBL2369051 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148422-A1 | BRIDGED COMPOUNDS AS KRAS G12D INHIBITOR AND DEGRADER AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2022-07-14 | — | — | WO | disclosed |