Bicarbonate

Bicarbonate

SCHEMBL236925

CC(C)Oc1ccccc1C(=O)O.CC(C)Oc1ccccc1C(=O)O.O=C(O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.68
KDM4E B2RXH2 9/20 0.58
HSD17B10 Q99714 7/20 0.58
HPGD P15428 5/20 0.58
ALDH1A1 P00352 10/20 0.56
ESR1 P03372 1/20 0.56
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
TSHR P16473 1/20 0.56
GGT1 P19440 1/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
RECQL P46063 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27809575 1.00 IRAK4 (0.68) IRAK4KDM4EHSD17B10HPGDALDH1A1
Bicarbonate SCHEMBL21811920 1.00 IRAK4 (0.68) IRAK4KDM4EHSD17B10HPGDALDH1A1
Bicarbonate SCHEMBL29943521 1.00 IRAK4 (0.68) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL104892 0.98 IRAK4 (0.70) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL10763308 0.96 IRAK4 (0.68) IRAK4KDM4EHSD17B10HPGDALDH1A1
Fumaric Acid SCHEMBL28397774 0.90 IRAK4 (0.60) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL234522 0.87 IRAK4 (0.57) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL28613229 0.87 IRAK4 (0.57) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL10619157 0.86 KDM4E (0.59) IRAK4KDM4EHSD17B10HPGDALDH1A1
SCHEMBL10337047 0.85 KDM4E (0.58) IRAK4KDM4EHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-3840958-B1 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS COVESTRO DEUTSCHLAND AG (DE) 2025-02-19 EP disclosed
EP-4493388-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-01-22 EP disclosed
EP-1742983-A1 PROCESS FOR PRODUCING POLYCARBONATE Bayer MaterialScience AG (DE) 2007-01-17 EP disclosed
EP-1692205-A1 METHOD FOR PRODUCING POLYCARBONATES HAVING A LOW CONTENT OF VOLATILE COMPOUNDS ACCORDING TO THE TRANSESTERIFICATION PROCESS Bayer MaterialScience AG (DE) 2006-08-23 EP disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
EP-1612231-A1 Inhibition of catalyst-active impurities in polycarbonate transesterification process Bayer MaterialScience AG (DE) 2006-01-04 EP disclosed
US-20050288407-A1 Thermally stabilized polycarbonate composition BAYER MATERIALSCIENCE AG 2005-12-29 US disclosed
EP-1609818-A2 Heat stabilised polycarbonate compositions Bayer MaterialScience AG (DE) 2005-12-28 EP disclosed
WO-2005103115-A1 PROCESS FOR PRODUCING POLYCARBONATE BAYER MATERIALSCIENCE AG (DE) 2005-11-03 WO disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed
WO-2005054335-A1 METHOD FOR PRODUCING POLYCARBONATES HAVING A LOW CONTENT OF VOLATILE COMPOUNDS ACCORDING TO THE TRANSESTERIFICATION PROCESS BAYER MATERIALSCIENCE AG (DE) 2005-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL IRAK4 2605/4885KDM4E 1997/4885HSD17B10 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.