Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.74 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490307 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL2518708 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL20067021 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL21800953 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL20740271 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL2802141 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL2145746 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL3443790 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL8981714 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 | |
| SCHEMBL17335289 | 1.00 | DGKA (0.74) | DGKANAAAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2538920-A1 | EMOLLIENT FOAMS FOR TREATMENT OF DERMATOSES | Precision Dermatology, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106026-A1 | EMOLLIENT FOAMS FOR TREATMENT OF DERMATOSES | PRECISION DERMATOLOGY, INC. (US) | 2011-09-01 | — | — | WO | disclosed |