Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838411 | 0.84 | ALDH1A1 (0.46) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL3569140 | 0.78 | CHKA (0.60) | CHRM3ALDH1A1KDM4EMEN1CHRM2 | |
| SCHEMBL30074040 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL23696908 | 0.78 | GPR6 (0.56) | ALDH1A1NPSR1KDM4ECHRM2KMT2A | |
| SCHEMBL28129028 | 0.78 | CHRM3 (0.43) | CHRM3FGFR3ALDH1A1NPSR1KDM4E | |
| SCHEMBL7652198 | 0.77 | ACVR1 (0.47) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17929345 | 0.77 | CXCR4 (0.56) | CHRM3ALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL23696897 | 0.77 | ALDH1A1 (0.50) | ALDH1A1NPSR1KDM4ETDP1 | |
| SCHEMBL2733863 | 0.77 | CYP1A2 (0.54) | ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL19585072 | 0.77 | CHKA (0.59) | CHRM3ALDH1A1KDM4EMEN1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147889-A1 | ISOINDOLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 康朴生物医药技术（上海）有限公司 | 2021-07-29 | — | — | WO | disclosed |