⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434773 | 1.00 | — | — | |
| SCHEMBL28153440 | 0.78 | — | — | |
| SCHEMBL17426112 | 0.76 | — | — | |
| SCHEMBL22986824 | 0.76 | — | — | |
| SCHEMBL15178028 | 0.76 | — | — | |
| SCHEMBL18383508 | 0.74 | — | — | |
| SCHEMBL2943922 | 0.73 | TDP1 (0.32) | — | |
| SCHEMBL15525400 | 0.70 | — | — | |
| Serine SCHEMBL17223963 | 0.70 | SLC1A1 (0.50) | — | |
| SCHEMBL602426 | 0.69 | GSR (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230111-A1 | PROSTAGLANDIN F2 ALPHA DERIVATIVES FOR DECREASING INTRAOCULAR PRESSURE | KOFF INVESTMENTS LLP (GB) | 2021-07-29 | — | — | US | disclosed |