⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534546 | 0.86 | ADORA2A (0.42) | — | |
| SCHEMBL21047589 | 0.85 | KMT2A (0.36) | — | |
| SCHEMBL976980 | 0.69 | TP53 (0.41) | — | |
| SCHEMBL4935890 | 0.67 | — | — | |
| SCHEMBL84841 | 0.67 | — | — | |
| SCHEMBL2845839 | 0.65 | — | — | |
| SCHEMBL6427468 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL29184275 | 0.65 | — | — | |
| Bromide SCHEMBL28393345 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL28392789 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103442568-A | Furo [3,2-d ] pyrimidine compounds | ABBVIE INC | 2013-12-11 | — | — | CN | claimed |
| CN-103442568-A | Furo [3,2-d ] pyrimidine compounds | ABBVIE INC | 2013-12-11 | — | — | CN | disclosed |
| EP-2545042-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112191-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-09-15 | — | — | WO | disclosed |