Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369862 | 0.86 | — | — | |
| SCHEMBL21047589 | 0.76 | KMT2A (0.36) | ALDH1A1MEN1KMT2AUSP2HSD17B10 | |
| SCHEMBL918020 | 0.68 | HTR6 (0.49) | SOS1CYP1A2ALDH1A1KDM1ACISD1 | |
| SCHEMBL1844542 | 0.68 | ALDH1A1 (0.72) | ALDH1A1KMT2AUSP2ALOX15 | |
| SCHEMBL13837808 | 0.68 | ALDH1A1 (0.48) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17911190 | 0.67 | HTR6 (0.50) | SOS1ALDH1A1KDM1ACISD1SLC6A2 | |
| SCHEMBL8372303 | 0.67 | CHRM5 (0.52) | ALDH1A1CHRM5CHRM3CHRM1CHRM2 | |
| SCHEMBL27712824 | 0.66 | HRH3 (0.47) | HRH3MAPK1CYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10465025 | 0.64 | PAK4 (0.43) | HRH3SOS1MAPK1CYP1A2CLK4 | |
| SCHEMBL11457761 | 0.64 | HTR2C (0.49) | HRH3CYP1A2CYP2D6KDM1AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099194-A1 | 4-(2-FUROYL)AMINOPIPERIDINE COMPOUND USEFUL AS THERAPEUTIC AGENT FOR ITCHING | KYORIN PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |